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A role for alternative splicing in circadian control of exocytosis and glucose homeostasis
The circadian clock is encoded by a negative transcriptional feedback loop that coordinates physiology and behavior through molecular programs that remain incompletely understood. Here, we reveal rhythmic genome-wide alternative splicing (AS) of pre-mRNAs encoding regulators of peptidergic secretion...
Autores principales: | Marcheva, Biliana, Perelis, Mark, Weidemann, Benjamin J., Taguchi, Akihiko, Lin, Haopeng, Omura, Chiaki, Kobayashi, Yumiko, Newman, Marsha V., Wyatt, Eugene J., McNally, Elizabeth M., Fox, Jocelyn E. Manning, Hong, Heekyung, Shankar, Archana, Wheeler, Emily C., Ramsey, Kathryn Moynihan, MacDonald, Patrick E., Yeo, Gene W., Bass, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397853/ https://www.ncbi.nlm.nih.gov/pubmed/32616519 http://dx.doi.org/10.1101/gad.338178.120 |
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