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Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution

RTEL1 helicase is a component of DNA repair and telomere maintenance machineries. While RTEL1's role in DNA replication is emerging, how RTEL1 preserves genomic stability during replication remains elusive. Here we used a range of proteomic, biochemical, cell, and molecular biology and gene edi...

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Detalles Bibliográficos
Autores principales: Björkman, Andrea, Johansen, Søren L., Lin, Lin, Schertzer, Mike, Kanellis, Dimitris C., Katsori, Anna-Maria, Christensen, Søren T., Luo, Yonglun, Andersen, Jens S., Elsässer, Simon J., Londono-Vallejo, Arturo, Bartek, Jiri, Schou, Kenneth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397856/
https://www.ncbi.nlm.nih.gov/pubmed/32561545
http://dx.doi.org/10.1101/gad.330050.119