Neural production of kynurenic acid in Caenorhabditis elegans requires the AAT-1 transporter

Kynurenic acid (KynA) levels link peripheral metabolic status to neural functions including learning and memory. Since neural KynA levels dampen learning capacity, KynA reduction has been proposed as a therapeutic strategy for conditions of cognitive deficit such as neurodegeneration. While KynA is...

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Detalles Bibliográficos
Autores principales: Lin, Lin, Lemieux, George A., Enogieru, Osatohanmwen Jessica, Giacomini, Kathleen M., Ashrafi, Kaveh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397858/
https://www.ncbi.nlm.nih.gov/pubmed/32675325
http://dx.doi.org/10.1101/gad.339119.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397858/
https://www.ncbi.nlm.nih.gov/pubmed/32675325
http://dx.doi.org/10.1101/gad.339119.120

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