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Neural production of kynurenic acid in Caenorhabditis elegans requires the AAT-1 transporter

Kynurenic acid (KynA) levels link peripheral metabolic status to neural functions including learning and memory. Since neural KynA levels dampen learning capacity, KynA reduction has been proposed as a therapeutic strategy for conditions of cognitive deficit such as neurodegeneration. While KynA is...

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Detalles Bibliográficos
Autores principales:	Lin, Lin, Lemieux, George A., Enogieru, Osatohanmwen Jessica, Giacomini, Kathleen M., Ashrafi, Kaveh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2020
Materias:	Research Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397858/ https://www.ncbi.nlm.nih.gov/pubmed/32675325 http://dx.doi.org/10.1101/gad.339119.120

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