Transcriptome-wide sites of collided ribosomes reveal principles of translational pausing

Translation initiation is the major regulatory step defining the rate of protein production from an mRNA. Meanwhile, the impact of nonuniform ribosomal elongation rates is largely unknown. Using a modified ribosome profiling protocol based on footprints from two closely packed ribosomes (disomes), w...

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Detalles Bibliográficos
Autores principales: Arpat, Alaaddin Bulak, Liechti, Angélica, De Matos, Mara, Dreos, René, Janich, Peggy, Gatfield, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397865/
https://www.ncbi.nlm.nih.gov/pubmed/32703885
http://dx.doi.org/10.1101/gr.257741.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397865/
https://www.ncbi.nlm.nih.gov/pubmed/32703885
http://dx.doi.org/10.1101/gr.257741.119

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