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Transcriptome-wide sites of collided ribosomes reveal principles of translational pausing
Translation initiation is the major regulatory step defining the rate of protein production from an mRNA. Meanwhile, the impact of nonuniform ribosomal elongation rates is largely unknown. Using a modified ribosome profiling protocol based on footprints from two closely packed ribosomes (disomes), w...
Autores principales: | Arpat, Alaaddin Bulak, Liechti, Angélica, De Matos, Mara, Dreos, René, Janich, Peggy, Gatfield, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397865/ https://www.ncbi.nlm.nih.gov/pubmed/32703885 http://dx.doi.org/10.1101/gr.257741.119 |
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