Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations

DNA-associated proteins (DAPs) classically regulate gene expression by binding to regulatory loci such as enhancers or promoters. As expanding catalogs of genome-wide DAP binding maps reveal thousands of loci that, unlike the majority of conventional enhancers and promoters, associate with dozens of...

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Detalles Bibliográficos
Autores principales: Ramaker, Ryne C., Hardigan, Andrew A., Goh, Say-Tar, Partridge, E. Christopher, Wold, Barbara, Cooper, Sara J., Myers, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397867/
https://www.ncbi.nlm.nih.gov/pubmed/32616518
http://dx.doi.org/10.1101/gr.260463.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397867/
https://www.ncbi.nlm.nih.gov/pubmed/32616518
http://dx.doi.org/10.1101/gr.260463.119

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