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TRACE: transcription factor footprinting using chromatin accessibility data and DNA sequence

Transcription is tightly regulated by cis-regulatory DNA elements where transcription factors (TFs) can bind. Thus, identification of TF binding sites (TFBSs) is key to understanding gene expression and whole regulatory networks within a cell. The standard approaches used for TFBS prediction, such a...

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Detalles Bibliográficos
Autores principales: Ouyang, Ningxin, Boyle, Alan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397869/
https://www.ncbi.nlm.nih.gov/pubmed/32660981
http://dx.doi.org/10.1101/gr.258228.119