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Irradiated mesenchymal stem cells support stemness maintenance of hepatocellular carcinoma stem cells through Wnt/β-catenin signaling pathway

BACKGROUND: Cancer stem cells are the main reason of relapse, metastasis and resistance to anti-cancer therapies of Hepatocellular carcinoma (HCC). Mesenchymal stem cells (MSCs) are an important part of the tumor microenvironment. MSCs have been demonstrated to be involved in drug resistance in tumo...

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Detalles Bibliográficos
Autores principales: Hou, Jing, Zhao, Naping, Zhu, Pengxi, Chang, Jun, Du, Yan, Shen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398068/
https://www.ncbi.nlm.nih.gov/pubmed/32774840
http://dx.doi.org/10.1186/s13578-020-00449-5