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Irradiated mesenchymal stem cells support stemness maintenance of hepatocellular carcinoma stem cells through Wnt/β-catenin signaling pathway
BACKGROUND: Cancer stem cells are the main reason of relapse, metastasis and resistance to anti-cancer therapies of Hepatocellular carcinoma (HCC). Mesenchymal stem cells (MSCs) are an important part of the tumor microenvironment. MSCs have been demonstrated to be involved in drug resistance in tumo...
Autores principales: | Hou, Jing, Zhao, Naping, Zhu, Pengxi, Chang, Jun, Du, Yan, Shen, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398068/ https://www.ncbi.nlm.nih.gov/pubmed/32774840 http://dx.doi.org/10.1186/s13578-020-00449-5 |
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