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Impact of body composition on outcomes from anti-PD1 +/− anti-CTLA-4 treatment in melanoma

BACKGROUND: Immune checkpoint inhibitors (ICIs) have transformed treatment for melanoma, but identifying reliable biomarkers of response and effective modifiable lifestyle factors has been challenging. Obesity has been correlated with improved responses to ICI, although the association of body compo...

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Detalles Bibliográficos
Autores principales: Young, Arissa C, Quach, Henry T, Song, Haocan, Davis, Elizabeth J, Moslehi, Javid J, Ye, Fei, Williams, Grant R, Johnson, Douglas B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398101/
https://www.ncbi.nlm.nih.gov/pubmed/32747470
http://dx.doi.org/10.1136/jitc-2020-000821