Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters

The human mechanosensitive ion channel PIEZO1 is gated by membrane tension and regulates essential biological processes such as vascular development and erythrocyte volume homeostasis. Currently, little is known about PIEZO1 plasma membrane localization and organization. Using a PIEZO1-GFP fusion pr...

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Detalles Bibliográficos
Autores principales: Ridone, Pietro, Pandzic, Elvis, Vassalli, Massimo, Cox, Charles D., Macmillan, Alexander, Gottlieb, Philip A., Martinac, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398139/
https://www.ncbi.nlm.nih.gov/pubmed/32582958
http://dx.doi.org/10.1085/jgp.201912515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398139/
https://www.ncbi.nlm.nih.gov/pubmed/32582958
http://dx.doi.org/10.1085/jgp.201912515

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