Intestinal CD8αα IELs derived from two distinct thymic precursors have staggered ontogeny

CD8αα intraepithelial lymphocytes (IELs) are abundant T cells that protect the gut epithelium. Their thymic precursors (IELps) include PD-1(+) type A and Tbet(+) type B populations, which differ in their antigen-receptor specificities. To better understand CD8αα IEL ontogeny, we performed “time-stam...

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Detalles Bibliográficos
Autores principales: Ruscher, Roland, Lee, S. Thera, Salgado, Oscar C., Breed, Elise R., Osum, Sara H., Hogquist, Kristin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398160/
https://www.ncbi.nlm.nih.gov/pubmed/32687575
http://dx.doi.org/10.1084/jem.20192336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398160/
https://www.ncbi.nlm.nih.gov/pubmed/32687575
http://dx.doi.org/10.1084/jem.20192336

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