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Talin1 sets the stage for dendritic cell activation

In this issue of JEM, Lim et al. (https://doi.org/10.1084/jem.20191810) provide exciting new evidence that talin1 plays an essential role in dendritic cell (DC) maturation and activation. Using conditional knockout mice, they demonstrate that talin1 promotes the formation of a preassembled TLR–Myddo...

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Detalles Bibliográficos
Autor principal: Clausen, Björn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398172/
https://www.ncbi.nlm.nih.gov/pubmed/32697285
http://dx.doi.org/10.1084/jem.20200574