cDC1 dysregulation in cancer: An opportunity for intervention

Conventional dendritic cells driven by the transcription factor Batf3 (cDC1 cells) are critical for the activation and maintenance of tumor-specific CD8(+) T cells. In this issue of JEM, Lin et al. (https://doi.org/10.1084/jem.20190673) demonstrate systemic dysfunction of cDC1 cells in pancreatic ca...

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Detalles Bibliográficos
Autores principales: Gajewski, Thomas F., Cron, Kyle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398176/
https://www.ncbi.nlm.nih.gov/pubmed/32697286
http://dx.doi.org/10.1084/jem.20200816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398176/
https://www.ncbi.nlm.nih.gov/pubmed/32697286
http://dx.doi.org/10.1084/jem.20200816

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