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Critical roles of super-enhancers in the pathogenesis of autoimmune diseases

The super-enhancer (SE) is a cluster of enhancers involved in cell differentiation via enhanced gene expression that determines cell identity. Meanwhile, genome-wide association studies (GWASs) have reported the presence of gene clusters containing single nucleotide polymorphisms (SNPs) susceptible...

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Detalles Bibliográficos
Autores principales: Yamagata, Kaoru, Nakayamada, Shingo, Tanaka, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398324/
https://www.ncbi.nlm.nih.gov/pubmed/32922569
http://dx.doi.org/10.1186/s41232-020-00124-9