SIRT3 protects against early brain injury following subarachnoid hemorrhage via promoting mitochondrial fusion in an AMPK dependent manner

BACKGROUND: Subarachnoid hemorrhage (SAH), an acute cerebrovascular accident, features with its high death and disability rate. Sirtuin3 (SIRT3) is a NAD+ dependent deacetylase which mainly located in mitochondria. Reduced SIRT3 function was indicated to involve in many disorders of central nervous...

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Detalles Bibliográficos
Autores principales: Wu, Xun, Luo, Jianing, Liu, Haixiao, Cui, Wenxing, Feng, Dayun, Qu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398350/
https://www.ncbi.nlm.nih.gov/pubmed/32922930
http://dx.doi.org/10.1186/s41016-019-0182-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398350/
https://www.ncbi.nlm.nih.gov/pubmed/32922930
http://dx.doi.org/10.1186/s41016-019-0182-7

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