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SIRT3 protects against early brain injury following subarachnoid hemorrhage via promoting mitochondrial fusion in an AMPK dependent manner

BACKGROUND: Subarachnoid hemorrhage (SAH), an acute cerebrovascular accident, features with its high death and disability rate. Sirtuin3 (SIRT3) is a NAD+ dependent deacetylase which mainly located in mitochondria. Reduced SIRT3 function was indicated to involve in many disorders of central nervous...

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Detalles Bibliográficos
Autores principales:	Wu, Xun, Luo, Jianing, Liu, Haixiao, Cui, Wenxing, Feng, Dayun, Qu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398350/ https://www.ncbi.nlm.nih.gov/pubmed/32922930 http://dx.doi.org/10.1186/s41016-019-0182-7

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