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HGF and IL-10 expressing ALB::GFP reporter cells generated from iPSCs show robust anti-fibrotic property in acute fibrotic liver model

BACKGROUND: Cell therapy using hepatocytes derived from stem cells has been regarded as a promising alternate to liver transplantation. However, the heterogeneity of these hepatocytes makes them unsuitable for therapeutic use. To overcome this limitation, we generated homogenous hepatocyte like indu...

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Detalles Bibliográficos
Autores principales: Choi, Ja Sung, Jeong, In Sil, Park, Young-Jin, Kim, Sung-Whan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398392/
https://www.ncbi.nlm.nih.gov/pubmed/32746905
http://dx.doi.org/10.1186/s13287-020-01745-0