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A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: a study of HIV-infected Zimbabwean adolescents

BACKGROUND: Adolescents experience higher levels of non-adherence to HIV treatment. Drug concentration in hair promises to be reliable for assessing exposure to antiretroviral (ARV) drugs. Pharmacokinetic modelling can explore utility of drug in hair. We aimed at developing and validating a pharmaco...

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Detalles Bibliográficos
Autores principales: Ngara, Bernard, Zvada, Simbarashe, Chawana, Tariro Dianah, Stray-Pedersen, Babill, Nhachi, Charles Fungai Brian, Rusakaniko, Simbarashe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398395/
https://www.ncbi.nlm.nih.gov/pubmed/32746923
http://dx.doi.org/10.1186/s40360-020-00437-y