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A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: a study of HIV-infected Zimbabwean adolescents
BACKGROUND: Adolescents experience higher levels of non-adherence to HIV treatment. Drug concentration in hair promises to be reliable for assessing exposure to antiretroviral (ARV) drugs. Pharmacokinetic modelling can explore utility of drug in hair. We aimed at developing and validating a pharmaco...
Autores principales: | Ngara, Bernard, Zvada, Simbarashe, Chawana, Tariro Dianah, Stray-Pedersen, Babill, Nhachi, Charles Fungai Brian, Rusakaniko, Simbarashe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398395/ https://www.ncbi.nlm.nih.gov/pubmed/32746923 http://dx.doi.org/10.1186/s40360-020-00437-y |
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