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Divergence of the PIERCE1 expression between mice and humans as a p53 target gene

PIERCE1, p53 induced expression 1 in Rb null cells, is a novel p53 target involved in the DNA damage response and cell cycle in mice. These facts prompted us to study the function of PIERCE1 with respect to p53-associated pathophysiology of cancer in humans. Unexpectedly, PIERCE1 did not respond to...

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Detalles Bibliográficos
Autores principales: Kim, Hye Jeong, Lee, Seung Eon, Na, Heeju, Roe, Jae-Seok, Roh, Jae-il, Lee, Han-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398528/
https://www.ncbi.nlm.nih.gov/pubmed/32745107
http://dx.doi.org/10.1371/journal.pone.0236881