Structure and catalytic mechanism of a human triglyceride synthesis enzyme

Triglycerides (triacylglycerols, TGs) store metabolic energy in organisms and have industrial uses for foods and fuels. Excessive accumulation of TGs in humans causes obesity and is associated with metabolic diseases(1). TG synthesis is catalyzed by acyl-CoA:diacylglycerol acyltransferase (DGAT) enz...

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Detalles Bibliográficos
Autores principales: Sui, Xuewu, Wang, Kun, Gluchowski, Nina L., Elliott, Shane D., Liao, Maofu, Walther, Tobias C., Farese, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398557/
https://www.ncbi.nlm.nih.gov/pubmed/32433611
http://dx.doi.org/10.1038/s41586-020-2289-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398557/
https://www.ncbi.nlm.nih.gov/pubmed/32433611
http://dx.doi.org/10.1038/s41586-020-2289-6

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