Host sirtuin 2 as an immunotherapeutic target against tuberculosis

Mycobacterium tuberculosis (Mtb) employs plethora of mechanisms to hijack the host defence machinery for its successful survival, proliferation and persistence. Here, we show that Mtb upregulates one of the key epigenetic modulators, NAD+ dependent histone deacetylase Sirtuin 2 (SIRT2), which upon i...

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Detalles Bibliográficos
Autores principales: Bhaskar, Ashima, Kumar, Santosh, Khan, Mehak Zahoor, Singh, Amit, Dwivedi, Ved Prakash, Nandicoori, Vinay Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398663/
https://www.ncbi.nlm.nih.gov/pubmed/32697192
http://dx.doi.org/10.7554/eLife.55415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398663/
https://www.ncbi.nlm.nih.gov/pubmed/32697192
http://dx.doi.org/10.7554/eLife.55415

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