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Trastuzumab Targeted Neratinib Loaded Poly-Amidoamine Dendrimer Nanocapsules for Breast Cancer Therapy

BACKGROUND: Human epidermal growth factor receptor2 (Her2) positive breast cancer represents 25% of breast cancer cases. Targeted therapy with Her2 monoclonal antibody, trastuzumab (TZ), represents the first-line treatment for this type of breast cancer. In addition, neratinib, an irreversible inhib...

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Detalles Bibliográficos
Autores principales: Aleanizy, Fadilah Sfouq, Alqahtani, Fulwah Yahya, Seto, Sara, Al Khalil, Nora, Aleshaiwi, Lama, Alghamdi, Manar, Alquadeib, Bushra, Alkahtani, Hamad, Aldarwesh, Amal, Alqahtani, Qamraa Hamad, Abdelhady, Hosam Gharib, Alsarra, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398757/
https://www.ncbi.nlm.nih.gov/pubmed/32801698
http://dx.doi.org/10.2147/IJN.S256898