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PRP4 Kinase Domain Loss Nullifies Drug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells

We have investigated the involvement of the pre-mRNA processing factor 4B (PRP4) kinase domain in mediating drug resistance. HCT116 cells were treated with curcumin, and apoptosis was assessed based on flow cytometry and the generation of reactive oxygen species (ROS). Cells were then transfected wi...

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Detalles Bibliográficos
Autores principales: Ahmed, Muhammad Bilal, Islam, Salman Ul, Sonn, Jong Kyung, Lee, Young Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398799/
https://www.ncbi.nlm.nih.gov/pubmed/32576716
http://dx.doi.org/10.14348/molcells.2020.2263