Cargando…

PRP4 Kinase Domain Loss Nullifies Drug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells

We have investigated the involvement of the pre-mRNA processing factor 4B (PRP4) kinase domain in mediating drug resistance. HCT116 cells were treated with curcumin, and apoptosis was assessed based on flow cytometry and the generation of reactive oxygen species (ROS). Cells were then transfected wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahmed, Muhammad Bilal, Islam, Salman Ul, Sonn, Jong Kyung, Lee, Young Sup
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398799/ https://www.ncbi.nlm.nih.gov/pubmed/32576716 http://dx.doi.org/10.14348/molcells.2020.2263

Ejemplares similares

PRP4 Induces Epithelial–Mesenchymal Transition and Drug Resistance in Colon Cancer Cells via Activation of p53
por: Islam, Salman Ul, et al.
Publicado: (2022)

PRPF overexpression induces drug resistance through actin cytoskeleton rearrangement and epithelial-mesenchymal transition
por: Islam, Salman Ul, et al.
Publicado: (2017)

Decursin negatively regulates LPS-induced upregulation of the TLR4 and JNK signaling stimulated by the expression of PRP4 in vitro
por: Ahmed, Muhammad Bilal, et al.
Publicado: (2020)

PRP4 Promotes Skin Cancer by Inhibiting Production of Melanin, Blocking Influx of Extracellular Calcium, and Remodeling Cell Actin Cytoskeleton
por: Ahmed, Muhammad Bilal, et al.
Publicado: (2021)

Lifespan reduction due to neoplasia is nullified by pseudoexfoliation syndrome
por: Slettedal, Jon Klokk, et al.
Publicado: (2018)

An Update on the Role of Dietary Phytochemicals in Human Skin Cancer: New Insights into Molecular Mechanisms
por: Islam, Salman Ul, et al.
Publicado: (2020)

Haploinsufficient tumor suppressor PRP4K is negatively regulated during epithelial‐to‐mesenchymal transition
por: Clarke, Livia E., et al.
Publicado: (2021)

Vast Amounts of Encoded Items Nullify but Do Not Reverse the Effect of Sleep on Declarative Memory
por: Kolibius, Luca D., et al.
Publicado: (2021)

Loss of profilin 2 contributes to enhanced epithelial-mesenchymal transition and metastasis of colorectal cancer
por: Zhang, Hui, et al.
Publicado: (2018)

Role of Epithelial to Mesenchymal Transition in Colorectal Cancer
por: Lu, Jian, et al.
Publicado: (2023)

Stress granules inhibit apoptosis by reducing ROS production, but this phenomenon is nullified by HTLV-1 Tax
por: Takahashi, Masahiko, et al.
Publicado: (2014)

Piperine, a Natural Bioenhancer, Nullifies the Antidiabetic and Antioxidant Activities of Curcumin in Streptozotocin-Diabetic Rats
por: Arcaro, Carlos Alberto, et al.
Publicado: (2014)

Phosphate-Solubilizing Bacteria Nullify the Antagonistic Effect of Soil Calcification on Bioavailability of Phosphorus in Alkaline Soils
por: Adnan, Muhammad, et al.
Publicado: (2017)

Coenzyme Q(10) nullified khat-induced hepatotoxicity, nephrotoxicity and inflammation in a mouse model
por: Kennedy, Chepukosi, et al.
Publicado: (2020)

A prolonged hiatus in postmenopausal HRT, does not nullify the therapy’s positive impact on ageing related sarcopenia
por: Onambélé-Pearson, Gladys L., et al.
Publicado: (2021)

Loss of the Krüppel-like factor 4 tumor suppressor is associated with epithelial-mesenchymal transition in colorectal cancer
por: Agbo, Kimberley C., et al.
Publicado: (2019)

Author Correction: Phosphate-Solubilizing Bacteria Nullify the Antagonistic Effect of Soil Calcification on Bioavailability of Phosphorus in Alkaline Soils
por: Adnan, Muhammad, et al.
Publicado: (2018)

Perspective of biopharmaceutics knowledge and practice of pharmacy personnel toward the effect of medication route and medical procedure on nullifying fasting
por: Oqal, Muna, et al.
Publicado: (2023)

TRIM37 promotes epithelial-mesenchymal transition in colorectal cancer
por: Hu, Cheng-En, et al.
Publicado: (2017)

Loss of Abhd5 Promotes Colorectal Tumor Development and Progression by Inducing Aerobic Glycolysis and Epithelial-Mesenchymal Transition
por: Ou, Juanjuan, et al.
Publicado: (2018)

Targeting Epithelial–Mesenchymal Transition (EMT) to Overcome Drug Resistance in Cancer
por: Du, Bowen, et al.
Publicado: (2016)

Role of the ABL tyrosine kinases in the epithelial–mesenchymal transition and the metastatic cascade
por: Luttman, Jillian Hattaway, et al.
Publicado: (2021)

Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells
por: Kumar, Anupam, et al.
Publicado: (2012)

Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis
por: Di Gregorio, Jacopo, et al.
Publicado: (2017)

Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition
por: Russell, Ronan, et al.
Publicado: (2015)

LIM protein JUB promotes epithelial–mesenchymal transition in colorectal cancer
por: Liang, Xing-Hua, et al.
Publicado: (2014)

Prognostic impact of histological categorisation of epithelial–mesenchymal transition in colorectal cancer
por: Ueno, H, et al.
Publicado: (2014)

Claudin-7 promotes the epithelial – mesenchymal transition in human colorectal cancer
por: Philip, Rahel, et al.
Publicado: (2014)

Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis
por: Chou, Chuan-Kai, et al.
Publicado: (2016)

Role of LOXL2 in the epithelial-mesenchymal transition and colorectal cancer metastasis
por: Park, Pil-Gu, et al.
Publicado: (2017)

HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer
por: Pudova, Elena A., et al.
Publicado: (2018)

Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer
por: Fan, Li-Ching, et al.
Publicado: (2016)

HOXD9 promote epithelial‐mesenchymal transition and metastasis in colorectal carcinoma
por: Liu, Mengwei, et al.
Publicado: (2020)

Genomics and prognosis analysis of epithelial-mesenchymal transition in colorectal cancer patients
por: Zhang, Zizhen, et al.
Publicado: (2020)

Visualization of epithelial-mesenchymal transition in an inflammatory microenvironment–colorectal cancer network
por: Ieda, Takeshi, et al.
Publicado: (2019)

Fibroblast growth factor-10 and epithelial-mesenchymal transition in colorectal cancer
por: Farajihaye Qazvini, Fatemeh, et al.
Publicado: (2019)

The Association Between Inflammation, Epithelial Mesenchymal Transition and Stemness in Colorectal Carcinoma
por: Briede, Inese, et al.
Publicado: (2020)

Epithelial-Mesenchymal Transition and MicroRNAs in Colorectal Cancer Chemoresistance to FOLFOX
por: Escalante, Paula I., et al.
Publicado: (2021)

Stemness, Inflammation and Epithelial–Mesenchymal Transition in Colorectal Carcinoma: The Intricate Network
por: Briede, Inese, et al.
Publicado: (2021)

The ceRNA network regulates epithelial-mesenchymal transition in colorectal cancer
por: Li, Ruina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bvtksalkpuo9rocdtpq8042b8i