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Enhancement of Antitumor Efficacy of Paclitaxel-Loaded PEGylated Liposomes by N,N-Dimethyl Tertiary Amino Moiety in Pancreatic Cancer

INTRODUCTION: Pancreatic cancer, or pancreatic duct adenocarcinoma (PDAC), remains one of the most lethal cancers and features insidious onset, highly aggressive behavior and early distant metastasis. The dense fibrotic stroma surrounding tumor cells is thought to be a shield to resist the permeatio...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Wang, Li, Luo, Shi, Hu, Jun, Huang, Xing, Li, Pei-Wen, Zhang, Yi, Wu, Chao, Tian, Bo-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398872/
https://www.ncbi.nlm.nih.gov/pubmed/32801636
http://dx.doi.org/10.2147/DDDT.S261017