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Therapeutic Effect of C-C Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis

OBJECTIVE AND DESIGN: Allergic rhinitis (AR) is an immunoglobulin E (IgE)-mediated inflammatory respiratory hypersensitivity characterized by elevated Th2 cytokines and infiltration of inflammatory cells to nasal tissues. BX471 is a small-molecule C-C chemokine receptor type 1 (CCR1) antagonist invo...

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Detalles Bibliográficos
Autores principales: Feng, Suoyi, Ju, Longzhu, Shao, Ziqi, Grzanna, Mark, Jia, Lu, Liu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398876/
https://www.ncbi.nlm.nih.gov/pubmed/32801828
http://dx.doi.org/10.2147/JIR.S254717