Cargando…

Therapeutic Effect of C-C Chemokine Receptor Type 1 (CCR1) Antagonist BX471 on Allergic Rhinitis

OBJECTIVE AND DESIGN: Allergic rhinitis (AR) is an immunoglobulin E (IgE)-mediated inflammatory respiratory hypersensitivity characterized by elevated Th2 cytokines and infiltration of inflammatory cells to nasal tissues. BX471 is a small-molecule C-C chemokine receptor type 1 (CCR1) antagonist invo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Suoyi, Ju, Longzhu, Shao, Ziqi, Grzanna, Mark, Jia, Lu, Liu, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398876/ https://www.ncbi.nlm.nih.gov/pubmed/32801828 http://dx.doi.org/10.2147/JIR.S254717

Ejemplares similares

Effects of blocking chemokine receptor CCR1 with BX471 in two models of fibrosis prevention and rescue in mice
por: Weber, Susanne N., et al.
Publicado: (2021)

Effects of a dual CCR3 and H(1)-antagonist on symptoms and eosinophilic inflammation in allergic rhinitis
por: Greiff, Lennart, et al.
Publicado: (2010)

Identification of C-C Chemokine Receptor 1 (CCR1) as the Monocyte Hemofiltrate C-C Chemokine (HCC)-1 Receptor
por: Tsou, Chia-Lin, et al.
Publicado: (1998)

The Relationship between Chemokine Ligand 3 and Allergic Rhinitis
por: Berghi, Ovidiu, et al.
Publicado: (2020)

Requirement for the Chemokine Receptor Ccr6 in Allergic Pulmonary Inflammation
por: Lukacs, Nicholas W., et al.
Publicado: (2001)

Screening of chemokine receptor CCR4 antagonists by capillary zone electrophoresis
por: Sun, Zhe, et al.
Publicado: (2011)

C-C Chemokine Receptor Seven (CCR7): Coming of Age In Vaccines
por: Bill, Colin A., et al.
Publicado: (2016)

lncRNA read-through regulates the BX-C insulator Fub-1
por: Ibragimov, Airat, et al.
Publicado: (2023)

Therapeutic Perspectives of HIV-Associated Chemokine Receptor (CCR5 and CXCR4) Antagonists in Carcinomas
por: González-Arriagada, Wilfredo Alejandro, et al.
Publicado: (2022)

A program finding the minimum over C of ||A + BxC ||
por: Leeb, K
Publicado: (1967)

Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10
por: Lim, Herman D., et al.
Publicado: (2021)

131 Expression of Chemokine Receptors CCR1, CCR3, CCR4, CCR5, CCR8 and CXCR3 in Human Nasal Polyps (NP); Comparison With NP From Allergic Patients With Aspirin Intolerance
por: Fundova, Petra, et al.
Publicado: (2012)

The Cytokine Nicotinamide Phosphoribosyltransferase (eNAMPT; PBEF; Visfatin) Acts as a Natural Antagonist of C-C Chemokine Receptor Type 5 (CCR5)
por: Torretta, Simone, et al.
Publicado: (2020)

Von Heyden 471
por: Jennings, A. H. P.
Publicado: (1925)

CCR3, CCR5, CCR8 and CXCR3 expression in memory T helper cells from allergic rhinitis patients, asymptomatically sensitized and healthy individuals
por: Holse, Mille, et al.
Publicado: (2006)

Internalization of the chemokine receptor CCR4 can be evoked by orthosteric and allosteric receptor antagonists
por: Ajram, Laura, et al.
Publicado: (2014)

The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity
por: Scheu, Stefanie, et al.
Publicado: (2017)

Dual systemic allergic rhinitis and local allergic rhinitis
por: Blanca, Miguel, et al.
Publicado: (2015)

Role of the Chemokine Receptors CCR1, CCR2 and CCR4 in the Pathogenesis of Experimental Dengue Infection in Mice
por: Guabiraba, Rodrigo, et al.
Publicado: (2010)

Chemokine (C-C Motif) Ligand 2/Chemokine Receptor 2 (CCR2) Axis Blockade to Delay Chondrocyte Hypertrophy as a Therapeutic Strategy for Osteoarthritis
por: Wang, Zidong, et al.
Publicado: (2021)

Stibosan (Von Heyden "471")
por: Napier, L. E.
Publicado: (1925)

Allergic rhinitis
por: Small, Peter, et al.
Publicado: (2011)

Allergic rhinitis
por: Small, Peter, et al.
Publicado: (2018)

Influence of Chemokine N-Terminal Modification on Biased Agonism at the Chemokine Receptor CCR1
por: Sanchez, Julie, et al.
Publicado: (2019)

C-C chemokine receptor type five (CCR5): An emerging target for the control of HIV infection()
por: Barmania, Fatima, et al.
Publicado: (2013)

Initiator Elements Function to Determine the Activity State of BX-C Enhancers
por: Iampietro, Carole, et al.
Publicado: (2010)

Associations of dietary vitamin A and C intake with asthma, allergic rhinitis, and allergic respiratory diseases
por: García-García, Carolina, et al.
Publicado: (2023)

The CCR2/MCP-1 Chemokine Pathway and Lung Adenocarcinoma
por: Mittal, Payal, et al.
Publicado: (2020)

Partial agonist activity of α(1)-adrenergic receptor antagonists for chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3
por: Gao, Xianlong, et al.
Publicado: (2018)

NOVEL THERAPEUTIC APPROACHES FOR ALLERGIC RHINITIS
por: Agosti, Jan M., et al.
Publicado: (2000)

C-C chemokine receptor type 5 (CCR5) utilization of transmitted and early founder human immunodeficiency virus type 1 envelopes and sensitivity to small-molecule CCR5 inhibitors
por: Hu, Qinxue, et al.
Publicado: (2010)

C-C chemokine receptor type 3 gene knockout alleviates inflammatory responses in allergic rhinitis model mice by regulating the expression of eosinophil granule proteins and immune factors
por: Zhu, Xinhua, et al.
Publicado: (2018)

Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5
por: Zhang, Hui, et al.
Publicado: (2021)

Increased benzoxazinoid (Bx) levels in wheat seedlings via jasmonic acid treatment and etiolation and their effects on Bx genes including Bx6
por: Sue, Masayuki, et al.
Publicado: (2021)

A Highly Selective Cc Chemokine Receptor (Ccr)8 Antagonist Encoded by the Poxvirus Molluscum Contagiosum
por: Lüttichau, Hans R., et al.
Publicado: (2000)

Targeting Chemokine Receptor CCR1 as a Potential Therapeutic Approach for Multiple Myeloma
por: Gilchrist, Annette, et al.
Publicado: (2022)

Management of Rhinitis: Allergic and Non-Allergic
por: Tran, Nguyen P, et al.
Publicado: (2011)

Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1
por: Shao, Zhehua, et al.
Publicado: (2021)

Séminaire Bourbaki : exposés 471–488
por: Collective
Publicado: (1977)

Natural Proteolytic Processing of Hemofiltrate Cc Chemokine 1 Generates a Potent Cc Chemokine Receptor (Ccr)1 and Ccr5 Agonist with Anti-HIV Properties
por: Detheux, Michel, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_cl4qfg3crnpj5davio00ug32qp