A systematic comparison of pharmacogene star allele calling bioinformatics algorithms: a focus on CYP2D6 genotyping

Genetic variation in genes encoding cytochrome P450 enzymes has important clinical implications for drug metabolism. Bioinformatics algorithms for genotyping these highly polymorphic genes using high-throughput sequence data and automating phenotype prediction have recently been developed. The CYP2D...

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Detalles Bibliográficos
Autores principales: Twesigomwe, David, Wright, Galen E. B., Drögemöller, Britt I., da Rocha, Jorge, Lombard, Zané, Hazelhurst, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398905/
https://www.ncbi.nlm.nih.gov/pubmed/32789024
http://dx.doi.org/10.1038/s41525-020-0135-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398905/
https://www.ncbi.nlm.nih.gov/pubmed/32789024
http://dx.doi.org/10.1038/s41525-020-0135-2

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