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Preclinical support for the therapeutic potential of zolmitriptan as a treatment for cocaine use disorders

Serotonin 1B receptor (5-HT(1B)R) agonists enhance cocaine intake in rats during daily self-administration but attenuate cocaine intake after prolonged abstinence. Here we investigated whether the less selective but clinically available 5-HT(1D/1B)R agonist, zolmitriptan, produces similar effects. M...

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Detalles Bibliográficos
Autores principales: Garcia, Raul, Le, Tien, Scott, Samantha N., Charmchi, Delaram, Sprout, Jamie M.L., Pentkowski, Nathan S., Neisewander, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398918/
https://www.ncbi.nlm.nih.gov/pubmed/32747623
http://dx.doi.org/10.1038/s41398-020-00956-6