Non-ischemic Heart Preservation via Hypothermic Cardioplegic Perfusion Induces Immunodepletion of Donor Hearts Resulting in Diminished Graft Infiltration Following Transplantation

Introduction: Many donor organs contain significant leukocyte reservoirs which upon transplantation activate recipient leukocytes to initiate acute rejection. We aimed to assess whether non-ischemic heart preservation via ex vivo perfusion promotes immunodepletion and alters the inflammatory status...

Descripción completa

Detalles Bibliográficos
Autores principales: Critchley, William R., Stone, John P., Liao, Qiuming, Qin, Guangqi, Risnes, Ivar, Trafford, Andrew, Scott, Helge, Sjöberg, Trygve, Steen, Stig, Fildes, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399062/
https://www.ncbi.nlm.nih.gov/pubmed/32849549
http://dx.doi.org/10.3389/fimmu.2020.01621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399062/
https://www.ncbi.nlm.nih.gov/pubmed/32849549
http://dx.doi.org/10.3389/fimmu.2020.01621

Ejemplares similares