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The GluN3 subunit regulates ion selectivity within native N-methyl-d-aspartate receptors

Glutamatergic N-methyl-d-aspartate receptors (NMDARs) are heterotetrameric proteins whose subunits are derived from three gene families, GRIN1 (codes for GluN1), GRIN2 (GluN2) and GRIN3 (GluN3). In addition to providing binding sites for glutamate and the co-agonist glycine, these subunits in their...

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Detalles Bibliográficos
Autores principales: Beesley, Stephen, Sullenberger, Thomas, Kumar, Sanjay S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399132/
https://www.ncbi.nlm.nih.gov/pubmed/32775760
http://dx.doi.org/10.1016/j.ibror.2020.07.009