Strategies to Enhance Logic Modeling-Based Cell Line-Specific Drug Synergy Prediction

Discrete dynamical modeling shows promise in prioritizing drug combinations for screening efforts by reducing the experimental workload inherent to the vast numbers of possible drug combinations. We have investigated approaches to predict combination responses across different cancer cell lines usin...

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Detalles Bibliográficos
Autores principales: Niederdorfer, Barbara, Touré, Vasundra, Vazquez, Miguel, Thommesen, Liv, Kuiper, Martin, Lægreid, Astrid, Flobak, Åsmund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399174/
https://www.ncbi.nlm.nih.gov/pubmed/32848834
http://dx.doi.org/10.3389/fphys.2020.00862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399174/
https://www.ncbi.nlm.nih.gov/pubmed/32848834
http://dx.doi.org/10.3389/fphys.2020.00862

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