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Drosophila Skp1 Homologue SkpA Plays a Neuroprotective Role in Adult Brain

Skp1, a component of the ubiquitin E3 ligases, was found to be decreased in the brains of sporadic Parkinson's disease (PD) patients, and its overexpression prevented death of murine neurons in culture. Here we expose the neuroprotective role of the Drosophila skp1 homolog, skpA, in the adult b...

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Detalles Bibliográficos
Autores principales: Dabool, Lital, Hakim-Mishnaevski, Ketty, Juravlev, Liza, Flint-Brodsly, Naama, Mandel, Silvia, Kurant, Estee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399183/
https://www.ncbi.nlm.nih.gov/pubmed/32739834
http://dx.doi.org/10.1016/j.isci.2020.101375