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Targeting Protein Kinase G to Treat Cardiac Proteotoxicity

Impaired or insufficient protein kinase G (PKG) signaling and protein quality control (PQC) are hallmarks of most forms of cardiac disease, including heart failure. Their dysregulation has been shown to contribute to and exacerbate cardiac hypertrophy and remodeling, reduced cell survival and diseas...

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Detalles Bibliográficos
Autores principales: Oeing, Christian U., Mishra, Sumita, Dunkerly-Eyring, Brittany L., Ranek, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399205/
https://www.ncbi.nlm.nih.gov/pubmed/32848832
http://dx.doi.org/10.3389/fphys.2020.00858