7-Hydroxycoumarin Attenuates Colistin-Induced Kidney Injury in Mice Through the Decreased Level of Histone Deacetylase 1 and the Activation of Nrf2 Signaling Pathway

Colistin has been considered as the last line of defense against Gram-negative bacterial infections, however, the potential nephrotoxicity limited its clinical use. 7-Hydroxycoumarin (7-HC) possesses many beneficial pharmacological activities. This study aimed to investigate the nephroprotective effe...

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Detalles Bibliográficos
Autores principales: Wang, Jian, Ishfaq, Muhammad, Fan, Qianqian, Chen, Chunli, Li, Jichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399215/
https://www.ncbi.nlm.nih.gov/pubmed/32848758
http://dx.doi.org/10.3389/fphar.2020.01146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399215/
https://www.ncbi.nlm.nih.gov/pubmed/32848758
http://dx.doi.org/10.3389/fphar.2020.01146

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