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Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome
Defects in mitochondrial function lead to severe neuromuscular orphan pathologies known as mitochondrial disease. Among them, Leigh Syndrome is the most common pediatric presentation, characterized by symmetrical brain lesions, hypotonia, motor and respiratory deficits, and premature death. Mitochon...
Autores principales: | Gella, Alejandro, Prada-Dacasa, Patricia, Carrascal, Montserrat, Urpi, Andrea, González-Torres, Melania, Abian, Joaquin, Sanz, Elisenda, Quintana, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399339/ https://www.ncbi.nlm.nih.gov/pubmed/32850799 http://dx.doi.org/10.3389/fcell.2020.00660 |
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