Development of a pH-responsive polymersome inducing endoplasmic reticulum stress and autophagy blockade

Autophagy is involved in the occurrence and development of tumors. Here, a pH-responsive polymersome codelivering hydroxychloroquine (HCQ) and tunicamycin (Tuni) drugs is developed to simultaneously induce endoplasmic reticulum (ER) stress and autophagic flux blockade for achieving an antitumor effe...

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Detalles Bibliográficos
Autores principales: Xu, Funeng, Li, Xilin, Huang, Xuehui, Pan, Jingmei, Wang, Yi, Zhou, Shaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399484/
https://www.ncbi.nlm.nih.gov/pubmed/32789182
http://dx.doi.org/10.1126/sciadv.abb8725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399484/
https://www.ncbi.nlm.nih.gov/pubmed/32789182
http://dx.doi.org/10.1126/sciadv.abb8725

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