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Development of a pH-responsive polymersome inducing endoplasmic reticulum stress and autophagy blockade

Autophagy is involved in the occurrence and development of tumors. Here, a pH-responsive polymersome codelivering hydroxychloroquine (HCQ) and tunicamycin (Tuni) drugs is developed to simultaneously induce endoplasmic reticulum (ER) stress and autophagic flux blockade for achieving an antitumor effe...

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Detalles Bibliográficos
Autores principales:	Xu, Funeng, Li, Xilin, Huang, Xuehui, Pan, Jingmei, Wang, Yi, Zhou, Shaobing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399484/ https://www.ncbi.nlm.nih.gov/pubmed/32789182 http://dx.doi.org/10.1126/sciadv.abb8725

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