BNIP-2 retards breast cancer cell migration by coupling microtubule-mediated GEF-H1 and RhoA activation

Microtubules display dynamic turnover during cell migration, leading to cell contractility and focal adhesion maturation regulated by Rho guanosine triphosphatase activity. This interplay between microtubules and actomyosin is mediated by guanine nucleotide exchange factor (GEF)–H1 released after mi...

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Detalles Bibliográficos
Autores principales: Pan, Meng, Chew, Ti Weng, Wong, Darren Chen Pei, Xiao, Jingwei, Ong, Hui Ting, Chin, Jasmine Fei Li, Low, Boon Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399486/
https://www.ncbi.nlm.nih.gov/pubmed/32789168
http://dx.doi.org/10.1126/sciadv.aaz1534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399486/
https://www.ncbi.nlm.nih.gov/pubmed/32789168
http://dx.doi.org/10.1126/sciadv.aaz1534

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