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Dorsoventral polarity directs cell responses to migration track geometries

How migrating cells differentially adapt and respond to extracellular track geometries remains unknown. Using intravital imaging, we demonstrate that invading cells exhibit dorsoventral (top-to-bottom) polarity in vivo. To investigate the impact of dorsoventral polarity on cell locomotion through di...

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Detalles Bibliográficos
Autores principales: Wisniewski, Emily O., Mistriotis, Panagiotis, Bera, Kaustav, Law, Robert A., Zhang, Jitao, Nikolic, Milos, Weiger, Michael, Parlani, Maria, Tuntithavornwat, Soontorn, Afthinos, Alexandros, Zhao, Runchen, Wirtz, Denis, Kalab, Petr, Scarcelli, Giuliano, Friedl, Peter, Konstantopoulos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399493/
https://www.ncbi.nlm.nih.gov/pubmed/32789173
http://dx.doi.org/10.1126/sciadv.aba6505