Cargando…
Dorsoventral polarity directs cell responses to migration track geometries
How migrating cells differentially adapt and respond to extracellular track geometries remains unknown. Using intravital imaging, we demonstrate that invading cells exhibit dorsoventral (top-to-bottom) polarity in vivo. To investigate the impact of dorsoventral polarity on cell locomotion through di...
Autores principales: | Wisniewski, Emily O., Mistriotis, Panagiotis, Bera, Kaustav, Law, Robert A., Zhang, Jitao, Nikolic, Milos, Weiger, Michael, Parlani, Maria, Tuntithavornwat, Soontorn, Afthinos, Alexandros, Zhao, Runchen, Wirtz, Denis, Kalab, Petr, Scarcelli, Giuliano, Friedl, Peter, Konstantopoulos, Konstantinos |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399493/ https://www.ncbi.nlm.nih.gov/pubmed/32789173 http://dx.doi.org/10.1126/sciadv.aba6505 |
Ejemplares similares
-
Confinement hinders motility by inducing RhoA-mediated nuclear influx, volume expansion, and blebbing
por: Mistriotis, Panagiotis, et al.
Publicado: (2019) -
The fluid shear stress sensor TRPM7 regulates tumor cell intravasation
por: Yankaskas, Christopher L., et al.
Publicado: (2021) -
Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement
por: Law, Robert A., et al.
Publicado: (2023) -
Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional area
por: Zhao, Runchen, et al.
Publicado: (2019) -
Hydraulic resistance induces cell phenotypic transition in confinement
por: Zhao, Runchen, et al.
Publicado: (2021)