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iPromoter-5mC: A Novel Fusion Decision Predictor for the Identification of 5-Methylcytosine Sites in Genome-Wide DNA Promoters

The hypomethylation of the whole cancer genome and the hypermethylation of the promoter of specific tumor suppressor genes are the important reasons for the rapid proliferation of cancer cells. Therefore, obtaining the distribution of 5-methylcytosine (5mC) in promoters is a key step to further unde...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Xiao, Xuan, Xu, Zhao-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399635/
https://www.ncbi.nlm.nih.gov/pubmed/32850787
http://dx.doi.org/10.3389/fcell.2020.00614