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Design and Evaluation of a Multiplexed Assay to Assess Human Immunogenicity Against Humira®

The use of biologic-based therapeutics has revolutionized our ability to treat complex diseases such as cancer- and autoimmune-related disorders. Biologic-based therapeutics are known to generate anti-drug immune responses or immunogenicity in clinical patients which can lead to altered pharmacokine...

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Detalles Bibliográficos
Autores principales: Alleyn, Matthew, Closson, Kristin, Gentile, Adam, Gulbis, Nathan, Taylor, Christopher, Rhyne, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399670/
https://www.ncbi.nlm.nih.gov/pubmed/32748082
http://dx.doi.org/10.1208/s12248-020-00487-4