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Design and Evaluation of a Multiplexed Assay to Assess Human Immunogenicity Against Humira®
The use of biologic-based therapeutics has revolutionized our ability to treat complex diseases such as cancer- and autoimmune-related disorders. Biologic-based therapeutics are known to generate anti-drug immune responses or immunogenicity in clinical patients which can lead to altered pharmacokine...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399670/ https://www.ncbi.nlm.nih.gov/pubmed/32748082 http://dx.doi.org/10.1208/s12248-020-00487-4 |