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Genetically programmed changes in transcription of the novel progranulin regulator

ABSTRACT: Progranulin is a glycoprotein marking chronic inflammation in obesity and type 2 diabetes. Previous studies suggested PSRC1 (proline and serine rich coiled-coil 1) to be a target of genetic variants associated with serum progranulin levels. We aimed to identify potentially functional varia...

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Detalles Bibliográficos
Autores principales: Keller, Maria, Gebhardt, Claudia, Huth, Sandra, Schleinitz, Dorit, Heyne, Henrike, Scholz, Markus, Stumvoll, Michael, Böttcher, Yvonne, Tönjes, Anke, Kovacs, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399677/
https://www.ncbi.nlm.nih.gov/pubmed/32620998
http://dx.doi.org/10.1007/s00109-020-01942-7