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Genetically programmed changes in transcription of the novel progranulin regulator
ABSTRACT: Progranulin is a glycoprotein marking chronic inflammation in obesity and type 2 diabetes. Previous studies suggested PSRC1 (proline and serine rich coiled-coil 1) to be a target of genetic variants associated with serum progranulin levels. We aimed to identify potentially functional varia...
Autores principales: | Keller, Maria, Gebhardt, Claudia, Huth, Sandra, Schleinitz, Dorit, Heyne, Henrike, Scholz, Markus, Stumvoll, Michael, Böttcher, Yvonne, Tönjes, Anke, Kovacs, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399677/ https://www.ncbi.nlm.nih.gov/pubmed/32620998 http://dx.doi.org/10.1007/s00109-020-01942-7 |
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