Vascular K(ATP) channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia

ABSTRACT: K(ATP) channels in the vasculature composed of Kir6.1 regulate vascular tone and may contribute to the pathogenesis of endotoxemia. We used mice with cell-specific deletion of Kir6.1 in smooth muscle (smKO) and endothelium (eKO) to investigate this question. We found that smKO mice had a s...

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Detalles Bibliográficos
Autores principales: Aziz, Qadeer, Chen, Jianmin, Moyes, Amie J, Li, Yiwen, Anderson, Naomi A, Ang, Richard, Aksentijevic, Dunja, Sebastian, Sonia, Hobbs, Adrian J, Thiemermann, Christoph, Tinker, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399691/
https://www.ncbi.nlm.nih.gov/pubmed/32632751
http://dx.doi.org/10.1007/s00109-020-01946-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399691/
https://www.ncbi.nlm.nih.gov/pubmed/32632751
http://dx.doi.org/10.1007/s00109-020-01946-3

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