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Vascular K(ATP) channels protect from cardiac dysfunction and preserve cardiac metabolism during endotoxemia
ABSTRACT: K(ATP) channels in the vasculature composed of Kir6.1 regulate vascular tone and may contribute to the pathogenesis of endotoxemia. We used mice with cell-specific deletion of Kir6.1 in smooth muscle (smKO) and endothelium (eKO) to investigate this question. We found that smKO mice had a s...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399691/ https://www.ncbi.nlm.nih.gov/pubmed/32632751 http://dx.doi.org/10.1007/s00109-020-01946-3 |